Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11507064 | 0.85 | MAPT (0.57) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL27668932 | 0.85 | MAPT (0.57) | MAPTALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL29566643 | 0.81 | MAPT (0.60) | MAPTALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL308233 | 0.81 | MAPT (0.60) | MAPTALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL3631214 | 0.81 | MAPT (0.60) | MAPTALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL738697 | 0.81 | MAPT (0.54) | MAPTALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL5028697 | 0.81 | MAPT (0.44) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL7973853 | 0.77 | KAT2B (0.66) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL9514664 | 0.77 | CHRM2 (0.51) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL3875390 | 0.76 | NPC1 (0.47) | CHRM2CHRM1DRD2ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204264-B1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| EP-0989123-A1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 2000-03-29 | — | — | EP | disclosed |