Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3039822 | 0.81 | RAB9A (0.43) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL3040719 | 0.77 | RAB9A (0.44) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL7973779 | 0.77 | CHRM2 (0.58) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL9515101 | 0.75 | SMN1; SMN2 (0.53) | PDE4DSMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL16861183 | 0.74 | RAB9A (0.48) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL9340103 | 0.73 | KMT2A (0.59) | ALDH1A1KMT2AMEN1PKMCA1 | |
| SCHEMBL3664450 | 0.73 | GPR35 (0.50) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL9550614 | 0.72 | CA2 (0.51) | ALDH1A1KMT2AMAPTMEN1PKM | |
| SCHEMBL4163164 | 0.72 | KMT2A (0.57) | ALDH1A1KMT2AMEN1CA1CA2 | |
| SCHEMBL10607041 | 0.71 | KMT2A (0.45) | SMN1; SMN2ALDH1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355735-B1 | Water soluble tripheno dioxazine compounds and their starting products containing sulfonyl groups, process for their preparation and use of these tripheno dioxazines as dyestuffs | HOECHST AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| US-5112970-A | Fiber reactive | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-12 | — | — | US | disclosed |