Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | CNOT7 | Q9UIV1 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PLEC | Q15149 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985608 | 0.94 | LMNA (0.53) | TNKSTNKS2PARP2CNOT7LMNA | |
| SCHEMBL7974613 | 0.92 | CNOT7 (0.49) | CNOT7LMNAKDM4EPOLBMAPK1 | |
| SCHEMBL7974505 | 0.89 | SMN1; SMN2 (0.55) | TNKSTNKS2PARP2CNOT7LMNA | |
| SCHEMBL7984680 | 0.88 | CNOT7 (0.43) | CNOT7LMNAKDM4EPOLBMAPK1 | |
| SCHEMBL7991672 | 0.88 | CNOT7 (0.46) | CNOT7LMNAKDM4EPOLBMAPK1 | |
| SCHEMBL7984240 | 0.85 | LMNA (0.58) | CNOT7LMNAKDM4EPOLBMAPK1 | |
| SCHEMBL7974274 | 0.84 | CNOT7 (0.45) | CNOT7LMNAKDM4EPOLBMAPK1 | |
| SCHEMBL7986518 | 0.84 | SMN1; SMN2 (0.53) | TNKSTNKS2PARP2CNOT7LMNA | |
| SCHEMBL7984488 | 0.83 | LMNA (0.53) | TNKSTNKS2CNOT7LMNAKDM4E | |
| SCHEMBL7986324 | 0.83 | HPGD (0.48) | CNOT7LMNAKDM4EPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |