Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984463 | 0.94 | KDM4E (0.53) | CNOT7SMN1; SMN2KMT2AHPGDMEN1 | |
| SCHEMBL7974644 | 0.89 | SMN1; SMN2 (0.55) | CNOT7SMN1; SMN2KMT2AHPGDMEN1 | |
| SCHEMBL7974613 | 0.85 | CNOT7 (0.49) | CNOT7SMN1; SMN2KMT2AHPGDKDM4E | |
| SCHEMBL7984480 | 0.85 | CNOT7 (0.47) | CNOT7SMN1; SMN2KMT2AHPGDMEN1 | |
| SCHEMBL7973869 | 0.84 | TNKS (0.46) | CNOT7SMN1; SMN2KMT2AHPGDMEN1 | |
| SCHEMBL7985444 | 0.84 | CNOT7 (0.41) | CNOT7SMN1; SMN2KMT2AHPGDMEN1 | |
| SCHEMBL7988183 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AHPGDMEN1KDM4E | |
| SCHEMBL7974278 | 0.82 | CNOT7 (0.53) | CNOT7SMN1; SMN2KMT2AHPGDMEN1 | |
| SCHEMBL7973916 | 0.82 | LMNA (0.43) | SMN1; SMN2KMT2AHPGDMEN1LMNA | |
| SCHEMBL7988452 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AHPGDMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |