Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 2/20 | 0.43 |
| ▸ | PARN | O95453 | 1/20 | 0.43 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PLEC | Q15149 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986518 | 0.95 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KMT2AHPGDTNKS | |
| SCHEMBL7984279 | 0.94 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1KMT2AHPGDTNKS | |
| SCHEMBL7975265 | 0.92 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1KMT2AHPGDTNKS | |
| SCHEMBL7988635 | 0.90 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1KMT2AHPGDTNKS | |
| SCHEMBL7975129 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1KMT2AHPGDTNKS | |
| SCHEMBL7984453 | 0.89 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1KMT2AHPGDTNKS | |
| SCHEMBL7988814 | 0.89 | MAPK1 (0.46) | SMN1; SMN2ALDH1A1KMT2AHPGDL3MBTL1 | |
| SCHEMBL7973869 | 0.89 | TNKS (0.46) | SMN1; SMN2ALDH1A1KMT2AHPGDTNKS | |
| SCHEMBL7985164 | 0.89 | KMT2A (0.46) | SMN1; SMN2ALDH1A1KMT2AHPGDTNKS | |
| Hydrochloric Acid SCHEMBL7985511 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1KMT2AHPGDTNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |