Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CNOT7 | Q9UIV1 | 7/20 | 0.39 |
| ▸ | PRCP | P42785 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985603 | 0.93 | CNOT7 (0.41) | ADORA3ADORA2AADORA1CNOT7PRCP | |
| SCHEMBL7974615 | 0.92 | ADORA2A (0.44) | ADORA3ADORA2AADORA1HTTCNOT7 | |
| SCHEMBL7974507 | 0.88 | MET (0.46) | ADORA3ADORA2ACNOT7ALDH1A1MET | |
| SCHEMBL7984683 | 0.88 | CNOT7 (0.37) | ADORA3ADORA2AADORA1HTTCNOT7 | |
| SCHEMBL7991678 | 0.87 | HTT (0.40) | ADORA3ADORA2AADORA1HTTCNOT7 | |
| SCHEMBL7984242 | 0.84 | CNOT7 (0.45) | ADORA3ADORA2AADORA1HTTCNOT7 | |
| SCHEMBL7974276 | 0.84 | HTT (0.39) | ADORA2AHTTCNOT7ALDH1A1MAPK14 | |
| SCHEMBL7986521 | 0.83 | CYP11B1 (0.47) | ADORA3ADORA2AALDH1A1MET | |
| SCHEMBL7984406 | 0.83 | CASR (0.43) | ADORA3ADORA2AADORA1HTTCNOT7 | |
| SCHEMBL7984490 | 0.82 | CNOT7 (0.41) | ADORA3ADORA2AADORA1CNOT7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |