Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974291 | 0.94 | CNOT7 (0.39) | CNOT7ADORA2AADORA1FAAHDPP4 | |
| SCHEMBL7984406 | 0.89 | CASR (0.43) | CNOT7HTTADORA2AADORA1ALDH1A1 | |
| SCHEMBL7987253 | 0.89 | HPGDS (0.40) | ADORA2AADORA1ALDH1A1ADORA3 | |
| SCHEMBL7974615 | 0.89 | ADORA2A (0.44) | CNOT7HTTADORA2AADORA1ALDH1A1 | |
| SCHEMBL7973871 | 0.88 | ADORA3 (0.40) | CNOT7HTTADORA2AADORA1ALDH1A1 | |
| SCHEMBL7988551 | 0.87 | ADORA3 (0.43) | CNOT7HTTADORA2AADORA1ALDH1A1 | |
| SCHEMBL7988583 | 0.87 | ALDH1A1 (0.41) | CNOT7HTTADORA2AADORA1ALDH1A1 | |
| SCHEMBL7991669 | 0.85 | HDAC1 (0.38) | — | |
| SCHEMBL7985791 | 0.84 | CYP11B1 (0.40) | ADORA2AALDH1A1ADORA3 | |
| SCHEMBL7989009 | 0.84 | GAA (0.47) | ADORA2AADORA1ALDH1A1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |