Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972727 | 1.00 | MEN1 (0.36) | MEN1KMT2AITGB3ITGA2BOPRM1 | |
| SCHEMBL7497904 | 1.00 | MEN1 (0.36) | MEN1KMT2AITGB3ITGA2BOPRM1 | |
| SCHEMBL7492543 | 0.83 | CYP2C9 (0.36) | CYP2C19CCR5ALDH1A1HTTCYP2C9 | |
| SCHEMBL7986267 | 0.83 | CYP2C9 (0.36) | CYP2C19CCR5ALDH1A1HTTCYP2C9 | |
| SCHEMBL7495961 | 0.83 | LMNA (0.49) | MEN1KMT2ACYP2C19KCNH2CCR5 | |
| SCHEMBL7931908 | 0.83 | LMNA (0.49) | MEN1KMT2ACYP2C19KCNH2CCR5 | |
| SCHEMBL7488769 | 0.80 | CCR5 (0.41) | MEN1KMT2AITGB3ITGA2BOPRM1 | |
| SCHEMBL7973519 | 0.80 | CCR5 (0.41) | MEN1KMT2AITGB3ITGA2BOPRM1 | |
| SCHEMBL7973894 | 0.80 | CCR5 (0.41) | MEN1KMT2AITGB3ITGA2BOPRM1 | |
| SCHEMBL7497446 | 0.76 | HRH3 (0.44) | SLC6A4KCNH2CCR5HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265434-B1 | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |