Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TTK | P33981 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | F9 | P00740 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961139 | 0.89 | F9 (0.47) | TTKF9F10F11F7 | |
| SCHEMBL20307797 | 0.85 | F9 (0.47) | ALDH1A1KDM4EF9F10F11 | |
| SCHEMBL10140109 | 0.82 | SMN1; SMN2 (0.44) | ALDH1A1KDM4EHPGDTP53HSD17B10 | |
| SCHEMBL7971260 | 0.81 | F9 (0.45) | ALDH1A1KDM4EHPGDTP53HSD17B10 | |
| SCHEMBL7971254 | 0.78 | F9 (0.41) | ALDH1A1KDM4EF9F10F11 | |
| SCHEMBL7978374 | 0.77 | F9 (0.54) | ALDH1A1MEN1KMT2AF9F10 | |
| SCHEMBL20307773 | 0.75 | F9 (0.43) | ALDH1A1KDM4EHPGDTP53HSD17B10 | |
| SCHEMBL7971532 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDTP53HSD17B10 | |
| SCHEMBL7974859 | 0.74 | F9 (0.68) | ALDH1A1KDM4EHPGDTP53HSD17B10 | |
| SCHEMBL7979892 | 0.73 | HPSE (0.47) | HPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |