Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 3/20 | 0.41 |
| ▸ | METAP1 | P53582 | 3/20 | 0.41 |
| ▸ | CBFB | Q13951 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974051 | 0.89 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KMT2AHPGDMETAP2 | |
| SCHEMBL7985490 | 0.88 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KMT2AHPGDMETAP2 | |
| SCHEMBL7992174 | 0.88 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2KMT2AHPGDMETAP2 | |
| SCHEMBL7991785 | 0.88 | HPGD (0.46) | ALDH1A1SMN1; SMN2KMT2AHPGDMETAP2 | |
| SCHEMBL7985787 | 0.86 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2KMT2AHPGDGAA | |
| SCHEMBL7985453 | 0.85 | GAA (0.52) | ALDH1A1SMN1; SMN2KMT2AHPGDHTT | |
| SCHEMBL7991667 | 0.85 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KMT2AHPGDMKNK1 | |
| SCHEMBL7988452 | 0.84 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2KMT2AHPGDGAA | |
| SCHEMBL7985261 | 0.84 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KMT2AHPGDMKNK1 | |
| SCHEMBL7988635 | 0.84 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KMT2AHPGDMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |