Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 2/20 | 0.44 |
| ▸ | PARN | O95453 | 1/20 | 0.44 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | METAP1 | P53582 | 2/20 | 0.43 |
| ▸ | KRAS | P01116 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974051 | 0.91 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KMT2AHPGDHTT | |
| SCHEMBL7991530 | 0.91 | HPGD (0.48) | ALDH1A1SMN1; SMN2KMT2AHPGDHTT | |
| SCHEMBL7992174 | 0.90 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2KMT2AHPGDHTT | |
| SCHEMBL7985285 | 0.88 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KMT2AHPGDHTT | |
| SCHEMBL7991785 | 0.88 | HPGD (0.46) | ALDH1A1SMN1; SMN2KMT2AHPGDHTT | |
| SCHEMBL7991655 | 0.88 | HPGD (0.46) | ALDH1A1SMN1; SMN2KMT2AHPGDHTT | |
| SCHEMBL7974003 | 0.88 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KMT2AHPGDHTT | |
| SCHEMBL7988799 | 0.86 | LMNA (0.54) | ALDH1A1SMN1; SMN2KMT2AHPGDHTT | |
| SCHEMBL7985453 | 0.86 | GAA (0.52) | ALDH1A1SMN1; SMN2KMT2AHPGDHTT | |
| SCHEMBL7975265 | 0.85 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2KMT2AHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |