Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988635 | 0.92 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KMT2AROCK2ROCK1 | |
| SCHEMBL7985787 | 0.92 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2KMT2AROCK2ROCK1 | |
| SCHEMBL7991667 | 0.90 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KMT2AROCK2ROCK1 | |
| SCHEMBL7985331 | 0.89 | GRIN1 (0.45) | ALDH1A1SMN1; SMN2KMT2AROCK2HPGD | |
| SCHEMBL7988745 | 0.88 | HPGD (0.44) | ALDH1A1SMN1; SMN2KMT2AROCK2ROCK1 | |
| SCHEMBL8056885 | 0.88 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2KMT2AHPGDGRIA1 | |
| SCHEMBL7985270 | 0.87 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KMT2AHPGDGRIA1 | |
| SCHEMBL7974445 | 0.87 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KMT2AHPGDGRIA1 | |
| SCHEMBL7985297 | 0.87 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KMT2AROCK2ROCK1 | |
| SCHEMBL7985359 | 0.86 | GRIN1 (0.45) | ALDH1A1SMN1; SMN2KMT2AHPGDMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |