SCHEMBL7974038

SCHEMBL7974038

COc1cc(Cl)c2[c]coc2c1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 3/20 0.33
MAOB P27338 6/20 0.33
MAOA P21397 4/20 0.33
GAA P10253 2/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
GLA P06280 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7974036 0.71 ALDH1A1 (0.34) ALDH1A1MAOBMAOA
SCHEMBL7972477 0.64 ALDH1A1 (0.34) ALDH1A1MAOBMAOA
SCHEMBL7976444 0.64 ALDH1A1 (0.34) ALDH1A1KDM4EGAAHPGDMEN1
SCHEMBL6011025 0.64 ALDH1A1 (0.34) ALDH1A1HPGDHSD17B10MEN1KMT2A
SCHEMBL1047515 0.64 ALDH1A1 (0.56) ALDH1A1GAAHPGDHSD17B10
SCHEMBL18207557 0.63 CYP1A2 (0.41) ALDH1A1MEN1KMT2A
SCHEMBL4462778 0.63 CYP1A2 (0.33) LMNA
SCHEMBL4116888 0.63 ALDH1A1 (0.42) ALDH1A1KDM4EMAOAHPGDHSD17B10
SCHEMBL2560197 0.62 ALDH1A1 (0.53) ALDH1A1KDM4EGAAHPGDHSD17B10
SCHEMBL8430640 0.62 ALDH1A1 (0.53) ALDH1A1KDM4EGAAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268514-B1 TREATING INDUSTRIAL MATERIALS WITH NITROETHANE COMPOUND FOR PROTECTING AGAINST ATTACK AND DESTRUCTION BY MICROORGANISMS BASF AKTIENGESELLSCHAFT (DE) 2001-07-31 US disclosed