SCHEMBL7976444

SCHEMBL7976444

COc1cc(Cl)c2[c]csc2c1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 2/20 0.31
MEN1 O00255 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
ALOX12 P18054 1/20 0.31
MPI P34949 1/20 0.31
HTT P42858 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5540318 0.78 NPC1 (0.32) PKMMPILMNAGAA
SCHEMBL7976442 0.71 ALDH1A1 (0.34) ALDH1A1KDM4EMEN1PKMHPGD
SCHEMBL5540638 0.68 ALDH1A1 (0.33) ALDH1A1HPGD
SCHEMBL8430640 0.67 ALDH1A1 (0.53) ALDH1A1KDM4EHPGDGAA
SCHEMBL4471499 0.67 PSMB8 (0.40) ALDH1A1KDM4EMEN1HTTKMT2A
SCHEMBL3648756 0.66 TUBB4A (0.38) ALDH1A1KDM4EMEN1HTTKMT2A
SCHEMBL7976066 0.64 ALDH1A1 (0.34) ALDH1A1KDM4EMEN1PKMHPGD
SCHEMBL6011025 0.64 ALDH1A1 (0.34) ALDH1A1MEN1HPGDKMT2A
SCHEMBL7974038 0.64 ALDH1A1 (0.34) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL1047515 0.64 ALDH1A1 (0.56) ALDH1A1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268514-B1 TREATING INDUSTRIAL MATERIALS WITH NITROETHANE COMPOUND FOR PROTECTING AGAINST ATTACK AND DESTRUCTION BY MICROORGANISMS BASF AKTIENGESELLSCHAFT (DE) 2001-07-31 US disclosed