SCHEMBL7972477

SCHEMBL7972477

COc1cc(Cl)c2[c]occ2c1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2A6 P11509 1/20 0.34
CYP1A1 P04798 2/20 0.32
CYP1B1 Q16678 2/20 0.32
NQO2 P16083 1/20 0.31
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
RELA Q04206 2/20 0.30
NFE2L2 Q16236 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18207557 0.70 CYP1A2 (0.41) ALDH1A1CYP1A2CYP2A6CYP1A1CYP1B1
SCHEMBL7976066 0.68 ALDH1A1 (0.34) ALDH1A1CYP1A2CYP2A6CYP1A1CYP1B1
SCHEMBL4477922 0.67 CYP2A6 (0.50) ALDH1A1CYP1A2CYP2A6CYP1A1CYP1B1
SCHEMBL4467165 0.65 CYP1A2 (0.39) ALDH1A1CYP1A2CYP2A6
SCHEMBL7974038 0.64 ALDH1A1 (0.34) ALDH1A1MAOAMAOB
SCHEMBL7972471 0.64 ALDH1A1 (0.34) ALDH1A1CYP1A2CYP2A6CYP1A1CYP1B1
SCHEMBL10897643 0.64 CYP1A2 (0.52) ALDH1A1CYP1A2CYP2A6NQO2
SCHEMBL1047515 0.64 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2A6CYP1A1CYP1B1
SCHEMBL4476964 0.63 CYP2A6 (0.50) ALDH1A1CYP1A2CYP2A6NQO2HSD17B1
SCHEMBL2560197 0.62 ALDH1A1 (0.53) ALDH1A1CYP1A2CYP2A6CYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268514-B1 TREATING INDUSTRIAL MATERIALS WITH NITROETHANE COMPOUND FOR PROTECTING AGAINST ATTACK AND DESTRUCTION BY MICROORGANISMS BASF AKTIENGESELLSCHAFT (DE) 2001-07-31 US disclosed