Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991877 | 0.96 | P2RX7 (0.47) | TP53RXFP1USP2CYP1A2CYP3A4 | |
| SCHEMBL7985852 | 0.93 | TP53 (0.52) | TP53RXFP1YTHDC1GAAMAPT | |
| SCHEMBL7974586 | 0.90 | GAA (0.52) | TP53RXFP1P2RX7GAAMAPT | |
| SCHEMBL7974021 | 0.90 | TP53 (0.51) | TP53RXFP1USP2CYP1A2CYP3A4 | |
| SCHEMBL7973628 | 0.90 | SMN1; SMN2 (0.48) | YTHDC1P2RX7CXCR2HTTGLA | |
| SCHEMBL7985655 | 0.90 | TP53 (0.48) | TP53RXFP1MEN1KMT2AYTHDC1 | |
| SCHEMBL7974316 | 0.89 | TP53 (0.48) | TP53RXFP1USP2CYP1A2CYP3A4 | |
| SCHEMBL7984697 | 0.89 | TP53 (0.48) | TP53RXFP1YTHDC1P2RX7GAA | |
| SCHEMBL7974015 | 0.88 | PARN (0.49) | USP2CYP1A2CYP2C9CYP2C19CXCR2 | |
| SCHEMBL7985381 | 0.88 | HPGD (0.48) | TP53RXFP1USP2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |