Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARN | O95453 | 1/20 | 0.49 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 3/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973628 | 0.96 | SMN1; SMN2 (0.48) | PARNCNOT7CXCR2PGRACP1 | |
| SCHEMBL7988669 | 0.94 | PARN (0.48) | PARNCNOT7CXCR2PGRACP1 | |
| SCHEMBL7985362 | 0.91 | GRIN1 (0.45) | PARNCNOT7CXCR2ACP1SMN1; SMN2 | |
| SCHEMBL7975243 | 0.91 | HTT (0.44) | PARNCNOT7CXCR2ACP1SMN1; SMN2 | |
| SCHEMBL7988553 | 0.90 | CNOT7 (0.50) | PARNCNOT7CXCR2PGRACP1 | |
| SCHEMBL7991600 | 0.90 | ACP1 (0.42) | PARNCNOT7CXCR2ACP1SMN1; SMN2 | |
| SCHEMBL7988784 | 0.90 | MAPK1 (0.43) | PARNCNOT7CXCR2ACP1SMN1; SMN2 | |
| SCHEMBL7975271 | 0.90 | CNOT7 (0.56) | PARNCNOT7CXCR2SMN1; SMN2PNP | |
| SCHEMBL7991568 | 0.89 | SMN1; SMN2 (0.45) | PARNCNOT7CXCR2ACP1SMN1; SMN2 | |
| SCHEMBL7984663 | 0.89 | CNOT7 (0.49) | PARNCNOT7SMN1; SMN2PNPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |