Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | CTSG | P08311 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.51 |
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7974167 | 0.98 | LMNA (0.56) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL18689914 | 0.85 | LMNA (0.69) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL14067433 | 0.84 | LMNA (0.62) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL3090568 | 0.83 | GAA (0.63) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL3192014 | 0.83 | LMNA (0.77) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL7960546 | 0.82 | L3MBTL1 (0.64) | LMNAGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7974114 | 0.81 | LMNA (0.59) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL17710353 | 0.81 | LMNA (0.59) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL7970760 | 0.81 | L3MBTL1 (0.62) | LMNAGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL3659106 | 0.80 | PRSS1 (0.66) | LMNAPOLBGAASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | claimed |