SCHEMBL7974147

SCHEMBL7974147

Cc1ccc(Cn2cncc2CN2CC(C)(C)Oc3c(C(=O)O)cccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FNTA P49354 11/20 0.42
FNTB P49356 11/20 0.42
CYP11B1 P15538 6/20 0.37
CYP11B2 P19099 6/20 0.37
PGGT1B P53609 3/20 0.36
FABP4 P15090 1/20 0.35
AMPD2 Q01433 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7971118 0.93 CYP11B1 (0.42) FNTAFNTBCYP11B1CYP11B2PGGT1B
SCHEMBL7971638 0.83 FNTA (0.47) FNTAFNTBCYP11B1CYP11B2PGGT1B
SCHEMBL7971733 0.77 KMT2A (0.41) FNTAFNTBCYP11B1CYP11B2PGGT1B
SCHEMBL7971101 0.75 FNTA (0.48) FNTAFNTBCYP11B1CYP11B2PGGT1B
SCHEMBL7968423 0.74 FNTA (0.49) FNTAFNTBCYP11B1CYP11B2PGGT1B
SCHEMBL7968966 0.71 FNTA (0.44) FNTAFNTBCYP11B1CYP11B2PGGT1B
SCHEMBL9484794 0.69 MYC (0.37) FABP4
SCHEMBL7972164 0.69 ITGA4 (0.40) FNTAFNTBCYP11B1CYP11B2
SCHEMBL7967527 0.69 FNTA (0.44) FNTAFNTBCYP11B1CYP11B2PGGT1B
SCHEMBL7971545 0.68 FNTA (0.47) FNTAFNTBCYP11B1CYP11B2PGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001009127-A1 BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE AVENTIS PHARMA S.A. (FR) 2001-02-08 WO disclosed