Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 9/20 | 0.41 |
| ▸ | FNTB | P49356 | 7/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967527 | 0.92 | FNTA (0.44) | KMT2AMEN1LMNAMAPTFNTA | |
| SCHEMBL7971545 | 0.91 | FNTA (0.47) | KMT2AMEN1LMNAMAPTFNTA | |
| SCHEMBL7971638 | 0.82 | FNTA (0.47) | MAPTFNTAFNTBPGGT1BCYP11B1 | |
| SCHEMBL7974147 | 0.77 | FNTA (0.42) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7971101 | 0.74 | FNTA (0.48) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7968423 | 0.73 | FNTA (0.49) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7971118 | 0.70 | CYP11B1 (0.42) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7968966 | 0.70 | FNTA (0.44) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7971730 | 0.69 | CPA1 (0.37) | KMT2AALDH1A1TP53POLBGAA | |
| SCHEMBL7972164 | 0.68 | ITGA4 (0.40) | MAPTFNTAFNTBALDH1A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |