Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.55 |
| ▸ | F9 | P00740 | 1/20 | 0.55 |
| ▸ | F11 | P03951 | 1/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 6/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | CBFB | Q13951 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974859 | 0.89 | F9 (0.68) | F10F9F11F7CHEK2 | |
| SCHEMBL7978374 | 0.85 | F9 (0.54) | F10F9F11F7CHEK2 | |
| SCHEMBL7970846 | 0.80 | CHEK2 (0.44) | CHEK2NPBWR1NT5ESLC2A1FGFR1 | |
| SCHEMBL7974790 | 0.78 | F10 (0.48) | F10F9F11F7CHEK2 | |
| SCHEMBL20307797 | 0.77 | F9 (0.47) | F10F9F11F7CHEK2 | |
| SCHEMBL7978435 | 0.74 | F10 (0.83) | F10F9F11F7F2 | |
| SCHEMBL7961139 | 0.74 | F9 (0.47) | F10F9F11F7CDK2 | |
| SCHEMBL7960247 | 0.72 | F9 (0.60) | F10F9F11F7CHEK2 | |
| SCHEMBL7971260 | 0.72 | F9 (0.45) | F10F9F11F7CHEK2 | |
| SCHEMBL3533865 | 0.72 | ITK (0.67) | CHEK2ITKFGFR1FGFR3FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |