Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.48 |
| ▸ | F9 | P00740 | 1/20 | 0.48 |
| ▸ | F11 | P03951 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | CBFB | Q13951 | 4/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.35 |
| ▸ | JAK1 | P23458 | 3/20 | 0.35 |
| ▸ | TYK2 | P29597 | 3/20 | 0.35 |
| ▸ | JAK3 | P52333 | 3/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCND3 | P30281 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969756 | 0.82 | F10 (0.42) | F10F9F11F7CBFB | |
| SCHEMBL7978374 | 0.82 | F9 (0.54) | F10F9F11F7NPBWR1 | |
| SCHEMBL7974859 | 0.82 | F9 (0.68) | F10F9F11F7CBFB | |
| SCHEMBL7974191 | 0.78 | F10 (0.55) | F10F9F11F7CBFB | |
| SCHEMBL16258910 | 0.78 | CBFB (0.40) | F10F9F11CBFBNPBWR1 | |
| SCHEMBL20307797 | 0.74 | F9 (0.47) | F10F9F11F7NPBWR1 | |
| SCHEMBL16258935 | 0.73 | CBFB (0.43) | F10F9F11CBFBNPBWR1 | |
| SCHEMBL20307768 | 0.72 | CBFB (0.42) | F10CBFBNPBWR1CHEK2F2 | |
| SCHEMBL10139920 | 0.71 | CBFB (0.46) | F10CBFBF2PLGPLAU | |
| SCHEMBL7973898 | 0.69 | ALDH1A1 (0.44) | F10F9F11F7CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |