Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | USP9X | Q93008 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417607 | 0.84 | ESR2 (0.45) | KMT2AMEN1MAPTESR2 | |
| SCHEMBL7985524 | 0.80 | ALDH1A1 (0.39) | KMT2AALDH1A1SMN1; SMN2LMNAUSP2 | |
| SCHEMBL1418084 | 0.74 | KMT2A (0.35) | KMT2AALDH1A1SMN1; SMN2LMNAUSP2 | |
| SCHEMBL1419555 | 0.73 | KMT2A (0.37) | KMT2AALDH1A1SMN1; SMN2LMNAUSP2 | |
| SCHEMBL12670983 | 0.73 | MEN1 (0.40) | KMT2AALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL12670984 | 0.70 | MEN1 (0.42) | KMT2AALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL7974241 | 0.67 | MEN1 (0.45) | KMT2AALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL29383213 | 0.67 | MAPT (0.50) | MAPTESR2 | |
| SCHEMBL7991790 | 0.65 | GAA (0.40) | KMT2AALDH1A1SMN1; SMN2LMNAUSP2 | |
| SCHEMBL21257533 | 0.65 | USP9X (0.46) | USP9XESR2MMP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |