Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985568 | 0.91 | CNOT7 (0.41) | CYP11B1CYP11B2HPGDTSHRCNOT7 | |
| SCHEMBL7974270 | 0.90 | ALDH1A1 (0.46) | ALDH1A1CYP11B1CYP11B2HPGDTSHR | |
| SCHEMBL7985342 | 0.90 | CNOT7 (0.51) | ALDH1A1HPGDCNOT7PARNSMN1; SMN2 | |
| SCHEMBL7991561 | 0.89 | HPGD (0.43) | ALDH1A1CYP11B1CYP11B2HPGDTSHR | |
| SCHEMBL7975243 | 0.88 | HTT (0.44) | ALDH1A1CYP11B1CYP11B2HPGDTSHR | |
| SCHEMBL7991647 | 0.88 | SMN1; SMN2 (0.44) | CNOT7PARNHTTSMN1; SMN2ACP1 | |
| SCHEMBL7988962 | 0.88 | GRIN1 (0.44) | ALDH1A1CYP11B1CYP11B2HPGDTSHR | |
| SCHEMBL7991638 | 0.88 | GRIN1 (0.42) | CNOT7PARNACP1MTORIDO1 | |
| SCHEMBL7988597 | 0.88 | PARN (0.48) | ALDH1A1CYP11B1CYP11B2HPGDCNOT7 | |
| SCHEMBL7984697 | 0.87 | TP53 (0.48) | LMNAGAAMTORMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |