Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991676 | 0.93 | ACP1 (0.43) | GRIN1GRIN2BP2RX7ACP1PARN | |
| SCHEMBL7974471 | 0.91 | ACP1 (0.43) | GRIN1GRIN2BHPGDPOLBMEN1 | |
| SCHEMBL7988570 | 0.91 | HPGD (0.47) | GRIN1GRIN2BHPGDPOLBMEN1 | |
| SCHEMBL7974270 | 0.90 | ALDH1A1 (0.46) | HPGDALDH1A1CYP11B1CYP11B2TSHR | |
| SCHEMBL7987255 | 0.90 | PARN (0.48) | GRIN1GRIN2BHPGDP2RX7ALDH1A1 | |
| SCHEMBL7991561 | 0.89 | HPGD (0.43) | HPGDMEN1KMT2AP2RX7ALDH1A1 | |
| SCHEMBL7975243 | 0.88 | HTT (0.44) | GRIN1GRIN2BHPGDPOLBP2RX7 | |
| SCHEMBL7987312 | 0.88 | GRIN1 (0.48) | GRIN1GRIN2BPOLBP2RX7HTT | |
| SCHEMBL7974249 | 0.88 | ALDH1A1 (0.41) | HPGDALDH1A1CYP11B1CYP11B2TSHR | |
| SCHEMBL7988597 | 0.88 | PARN (0.48) | HPGDKMT2AP2RX7ALDH1A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |