Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 6/20 | 0.51 |
| ▸ | PARN | O95453 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991647 | 0.92 | SMN1; SMN2 (0.44) | CNOT7PARNSMN1; SMN2 | |
| SCHEMBL7988790 | 0.91 | CNOT7 (0.53) | CNOT7PARNALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7985568 | 0.91 | CNOT7 (0.41) | CNOT7PARNSMN1; SMN2HPGD | |
| SCHEMBL7985619 | 0.91 | CNOT7 (0.41) | CNOT7PARNALDH1A1 | |
| SCHEMBL7974249 | 0.90 | ALDH1A1 (0.41) | CNOT7PARNALDH1A1SMN1; SMN2CXCR2 | |
| SCHEMBL7991638 | 0.90 | GRIN1 (0.42) | CNOT7PARNCXCR2MTOR | |
| SCHEMBL7984409 | 0.89 | CNOT7 (0.53) | CNOT7PARNALDH1A1CXCR2PTPN1 | |
| SCHEMBL7975271 | 0.89 | CNOT7 (0.56) | CNOT7PARNALDH1A1SMN1; SMN2CXCR2 | |
| SCHEMBL7974282 | 0.88 | ABCC8 (0.43) | CNOT7PARN | |
| SCHEMBL7984663 | 0.88 | CNOT7 (0.49) | CNOT7PARNALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |