Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985536 | 0.94 | SMN1; SMN2 (0.42) | L3MBTL1CNOT7NPC1RAB9ALTA4H | |
| SCHEMBL7975252 | 0.80 | HPGD (0.45) | CNOT7SMN1; SMN2TSHRGAAALDH1A1 | |
| SCHEMBL7984482 | 0.77 | GBA1 (0.42) | L3MBTL1CNOT7NPC1RAB9ALTA4H | |
| SCHEMBL7973934 | 0.76 | CYP11B1 (0.45) | SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL7985082 | 0.75 | HTT (0.46) | CNOT7HTTLMNATSHRALDH1A1 | |
| SCHEMBL7985651 | 0.75 | CYP1A2 (0.41) | SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL7984512 | 0.74 | GAA (0.50) | LMNAGAA | |
| SCHEMBL7988883 | 0.74 | CYP11B1 (0.46) | L3MBTL1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7985770 | 0.74 | CNOT7 (0.50) | L3MBTL1CNOT7NPC1RAB9ALTA4H | |
| SCHEMBL7987235 | 0.73 | TSHR (0.46) | CNOT7TLR7HTTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |