Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.40 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989407 | 0.88 | HPGD (0.44) | CNOT7HPGDSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL7989377 | 0.87 | LMNA (0.44) | HPGDTLR7SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7988957 | 0.86 | MET (0.45) | HPGDTLR7SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7985861 | 0.85 | CNOT7 (0.44) | CNOT7TLR7SMN1; SMN2ALDH1A1PPARG | |
| SCHEMBL7985733 | 0.84 | MEN1 (0.47) | YTHDC1HPGDSMN1; SMN2ALDH1A1PPARG | |
| SCHEMBL7984746 | 0.84 | ABCC8 (0.46) | HPGDTLR7SMN1; SMN2ALDH1A1MET | |
| SCHEMBL7987609 | 0.82 | PDE4A (0.43) | HPGDSMN1; SMN2ALDH1A1POLBCYP11B1 | |
| SCHEMBL7991724 | 0.82 | SMN1; SMN2 (0.47) | YTHDC1SMN1; SMN2MAPK1HTTKDM4E | |
| SCHEMBL7989566 | 0.81 | HPGD (0.41) | CNOT7HPGDSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL7988660 | 0.81 | CYP11B1 (0.49) | HPGDSMN1; SMN2ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |