Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988590 | 0.94 | ALDH1A1 (0.53) | ALDH1A1HPGDSMN1; SMN2KMT2ACYP11B1 | |
| SCHEMBL7988745 | 0.92 | HPGD (0.44) | ALDH1A1HPGDSMN1; SMN2KMT2ACYP11B1 | |
| SCHEMBL7985232 | 0.92 | HPGD (0.44) | ALDH1A1HPGDSMN1; SMN2KMT2ACYP11B1 | |
| SCHEMBL7991556 | 0.91 | HPGD (0.43) | ALDH1A1HPGDSMN1; SMN2KMT2ACYP11B1 | |
| SCHEMBL7988564 | 0.91 | HPGD (0.47) | ALDH1A1HPGDSMN1; SMN2KMT2ACYP11B1 | |
| SCHEMBL7975238 | 0.90 | HPGD (0.45) | ALDH1A1HPGDSMN1; SMN2KMT2ACYP11B1 | |
| SCHEMBL7974245 | 0.90 | HPGD (0.45) | ALDH1A1HPGDSMN1; SMN2KMT2ACYP11B1 | |
| SCHEMBL7988952 | 0.90 | GRIN1 (0.43) | ALDH1A1HPGDSMN1; SMN2KMT2ACYP11B1 | |
| SCHEMBL7988931 | 0.89 | GRIN1 (0.44) | ALDH1A1HPGDSMN1; SMN2KMT2ACYP11B1 | |
| SCHEMBL7975265 | 0.89 | SMN1; SMN2 (0.61) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |