Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988745 | 0.89 | HPGD (0.44) | KMT2AMAPK14HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7984766 | 0.89 | HPGD (0.44) | NPY5RKMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7974266 | 0.89 | ALDH1A1 (0.50) | KMT2AHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL7985331 | 0.88 | GRIN1 (0.45) | GRIN1GRIN2BKMT2AHPGDALDH1A1 | |
| SCHEMBL7988656 | 0.88 | NPY5R (0.44) | GRIN1GRIN2BNPY5RKMT2AHPGD | |
| SCHEMBL7974283 | 0.88 | ALDH1A1 (0.53) | KMT2AHPGDALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL7987428 | 0.88 | ROCK2 (0.57) | NPY5RROCK2GAARXFP1 | |
| SCHEMBL7991556 | 0.86 | HPGD (0.43) | KMT2AHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL7974245 | 0.85 | HPGD (0.45) | KMT2AHPGDALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL7988952 | 0.85 | GRIN1 (0.43) | GRIN1GRIN2BKMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |