Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325460 | 0.95 | RAPGEF4 (0.50) | RAPGEF4MAPTGAAALDH1A1MEN1 | |
| SCHEMBL1921159 | 0.90 | RAPGEF4 (0.65) | RAPGEF4MAPTGAAALDH1A1MEN1 | |
| SCHEMBL29445703 | 0.90 | RAPGEF4 (0.65) | RAPGEF4MAPTGAAALDH1A1MEN1 | |
| SCHEMBL5667044 | 0.88 | RAPGEF4 (0.63) | RAPGEF4MAPTGAAALDH1A1MEN1 | |
| SCHEMBL30146931 | 0.88 | RAPGEF4 (0.63) | RAPGEF4MAPTGAAALDH1A1MEN1 | |
| SCHEMBL5028501 | 0.86 | RAPGEF4 (0.61) | RAPGEF4MAPTGAAALDH1A1MEN1 | |
| SCHEMBL1921480 | 0.84 | RAPGEF4 (0.59) | RAPGEF4MAPTGAAALDH1A1MEN1 | |
| SCHEMBL15478852 | 0.82 | RAPGEF4 (0.57) | RAPGEF4MAPTGAAALDH1A1MEN1 | |
| SCHEMBL20930891 | 0.82 | RAPGEF4 (0.67) | RAPGEF4MAPTGAAALDH1A1MEN1 | |
| SCHEMBL21037121 | 0.81 | RAPGEF4 (0.55) | RAPGEF4MAPTGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717435-B | Modifier for durable flame-retardant rubber material, preparation method of modifier, durable rubber material and preparation method of durable flame-retardant rubber material | 株洲时代新材料科技股份有限公司 | 2023-06-06 | — | — | CN | claimed |
| US-12037303-B2 | Method for preparing diaryl p-phenylenediamine compounds | SENNICS CO., LTD. (CN) | 2024-07-16 | — | — | US | disclosed |
| US-20240076264-A1 | METHOD FOR PREPARING DIARYL P-PHENYLENEDIAMINE COMPOUNDS | SENNICS CO., LTD. (CN) | 2024-03-07 | — | — | US | disclosed |
| CN-113454153-B | In-line ultrasonic inspection for detecting partial vulcanization of rubber mixtures in-situ silylation of light-colored fillers | 朗盛德国有限责任公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-113717435-A | Modifier for durable flame-retardant rubber material, preparation method of modifier, durable rubber material and preparation method of durable rubber material | 株洲时代新材料科技股份有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-108603000-B | Method for testing in situ silanization of bright fillers | 朗盛德国有限责任公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-113454153-A | On-line ultrasonic inspection for detecting partial vulcanization of rubber mixtures in-situ silanization of light-colored fillers | 朗盛德国有限责任公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-102596539-B | Cross-linking agent batch containing marking substances, novel cross-linkable rubber mixtures, method for the production thereof and use thereof | RHEIN CHEMIE RHEINAU GMBH (DE) | 2015-09-30 | — | — | CN | disclosed |
| CN-102083893-B | Method and device for producing a cross-linkable rubber mixture | RHEIN CHEMIE RHEINAU GMBH | 2014-07-16 | — | — | CN | disclosed |
| CN-102596539-A | Cross-linking agent batch containing marking substances, novel cross-linkable rubber mixtures, method for the production thereof and use thereof | RHEIN CHEMIE RHEINAU GMBH | 2012-07-18 | — | — | CN | disclosed |
| US-6274666-B1 | COPOLYMER OF VINYL AROMATIC HYDROCARBON AND CONJUGATED DIENE | BRIDGESTONE/FIRESTONE, INC. | 2001-08-14 | — | — | US | disclosed |
| EP-0659787-B1 | Block copolymers and high shear strength pressure sensitive adhesive compositions comprising them | SHELL INT RESEARCH (NL) | 2000-09-20 | — | — | EP | disclosed |
| EP-0696603-B1 | Improved adhesive and polymer for adhesives | BRIDGESTONE FIRESTONE INC (US) | 1999-10-13 | — | — | EP | disclosed |
| EP-0696603-A1 | Improved adhesive and polymer for adhesives | BRIDGESTONE/FIRESTONE, INC. (US) | 1996-02-14 | — | — | EP | disclosed |
| EP-0659787-A1 | Block copolymers and high shear strength pressure sensitive adhesive compositions comprising them | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1995-06-28 | — | — | EP | disclosed |
| EP-0243956-B1 | ADHESIVE COMPOSITIONS | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4792584-A | BLOCK COPOLYMER OF BUTADIENE AND VINYL AROMATIC HYDROCARBON, TACKIFIER | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1988-12-20 | — | — | US | disclosed |
| EP-0243956-A2 | Adhesive compositions | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1987-11-04 | — | — | EP | disclosed |
| US-4256669-A | SOLVENT EXTRACTION AND ALKYLATION WITH AROMATIC AMINE TO PRODUCE DIARYL PARA-PHENYLENEDIAMINES | MALLINCKRODT, INC. (US) | 1981-03-17 | — | — | US | disclosed |
| US-4224247-A | Recovery of para-aminophenol | MALLINCKRODT, INC. (US) | 1980-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240076264-A1 | METHOD FOR PREPARING DIARYL P-PHENYLENEDIAMINE COMPOUNDS | C9, C1S, CCND2 | RAPGEF4 3130/4885MAPT 4295/4885GAA 3999/4885 |
| US-12037303-B2 | Method for preparing diaryl p-phenylenediamine compounds | C9, C1S, CCND2 | RAPGEF4 3130/4885MAPT 4295/4885GAA 3999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.