Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961134 | 0.82 | HCAR2 (0.31) | — | |
| SCHEMBL7972951 | 0.77 | LMNA (0.39) | ALDH1A1LMNA | |
| SCHEMBL7974750 | 0.74 | SIGMAR1 (0.41) | — | |
| SCHEMBL7972650 | 0.74 | — | — | |
| SCHEMBL7974425 | 0.74 | — | — | |
| SCHEMBL7220330 | 0.73 | TSHR (0.62) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL7961373 | 0.73 | CA2 (0.33) | — | |
| SCHEMBL7971417 | 0.73 | KDM4E (0.34) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL23292807 | 0.73 | TSHR (0.56) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL23292777 | 0.73 | TSHR (0.56) | TSHRKDM4EUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |