Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH1 | P20839 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.33 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | PPARD | Q03181 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 6/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974482 | 0.85 | ALDH1A1 (0.39) | IMPDH1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7971185 | 0.72 | EPHX2 (0.40) | IMPDH1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL798044 | 0.69 | CYP4F2 (0.53) | ALDH1A1MEN1KMT2APOLBMAPK1 | |
| SCHEMBL7974447 | 0.67 | CYP4F2 (0.43) | ALDH1A1MEN1KMT2APOLBMAPK1 | |
| SCHEMBL798335 | 0.67 | CYP4F2 (0.47) | ALDH1A1MEN1KMT2APOLBMAPK1 | |
| SCHEMBL798228 | 0.67 | CYP4F2 (0.47) | ALDH1A1MEN1KMT2APOLBMAPK1 | |
| SCHEMBL798312 | 0.67 | CYP4F2 (0.47) | ALDH1A1MEN1KMT2APOLBMAPK1 | |
| SCHEMBL17891898 | 0.66 | MAPK1 (0.40) | ALDH1A1MEN1KMT2APOLBMAPK1 | |
| SCHEMBL8140346 | 0.64 | POLB (0.38) | MEN1KMT2APOLBMAPK1SMN1; SMN2 | |
| SCHEMBL8968023 | 0.64 | CYP4F2 (0.71) | ALDH1A1MEN1KMT2AGPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| EP-0968164-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998033758-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-06 | — | — | WO | disclosed |