Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977541 | 0.88 | CYP4F2 (0.35) | CYP4F2CYP4A11CYP3A4TDP1KMT2A | |
| SCHEMBL7961051 | 0.88 | ALDH1A1 (0.37) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL7974475 | 0.81 | CYP4F2 (0.43) | CYP4F2CYP4A11LMNAMAPTPGR | |
| SCHEMBL7977575 | 0.79 | RAB9A (0.46) | LMNACYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL7974599 | 0.79 | CYP4F2 (0.44) | CYP4F2CYP4A11LMNAMAPTMAPK1 | |
| SCHEMBL7972852 | 0.75 | LMNA (0.44) | CYP4F2CYP4A11LMNAMAPTPGR | |
| SCHEMBL7971104 | 0.72 | APEX1 (0.36) | CYP4F2CYP4A11LMNAMAPTPGR | |
| SCHEMBL798044 | 0.72 | CYP4F2 (0.53) | CYP4F2CYP4A11LMNAMAPTMAPK1 | |
| SCHEMBL22098179 | 0.71 | CYP4F2 (0.63) | CYP4F2CYP4A11LMNAMAPTMAPK1 | |
| SCHEMBL7971401 | 0.70 | LMNA (0.40) | LMNAMAPTPGRCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |