Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 6/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.38 |
| ▸ | HTR2B | P41595 | 4/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991452 | 1.00 | REN (0.39) | RENHRH3ADRA2AHTR2AADRA1A | |
| SCHEMBL7853609 | 1.00 | REN (0.39) | RENHRH3ADRA2AHTR2AADRA1A | |
| SCHEMBL6974165 | 0.78 | OPRL1 (0.42) | HRH3ADRA2AADRA1AHTR1ALMNA | |
| SCHEMBL6974169 | 0.78 | OPRL1 (0.42) | HRH3ADRA2AADRA1AHTR1ALMNA | |
| SCHEMBL8508323 | 0.78 | OPRL1 (0.42) | HRH3ADRA2AADRA1AHTR1ALMNA | |
| SCHEMBL6979034 | 0.78 | OPRL1 (0.42) | HRH3ADRA2AADRA1AHTR1ALMNA | |
| SCHEMBL7872456 | 0.78 | OPRL1 (0.42) | HRH3ADRA2AADRA1AHTR1ALMNA | |
| SCHEMBL7352491 | 0.76 | REN (0.51) | REN | |
| SCHEMBL7352495 | 0.76 | REN (0.51) | REN | |
| SCHEMBL7987714 | 0.76 | IDO1 (0.39) | ADRA1AGRIN2BGRIN1GRIN2DGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307061-B2 | USEFUL AS AN ANALGESIC, ANESTHETIC, ANTI-INFLAMMATORY OR NEUROPROTECIVE AGENT | PFIZER INC. | 2001-10-23 | — | — | US | disclosed |