Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22875083 | 0.76 | LMNA (0.46) | CYP1A2CYP3A4CYP2D6TSHRGRIN2D | |
| SCHEMBL7974540 | 0.76 | REN (0.39) | CYP1A2CYP3A4CYP2D6TSHRGRIN2D | |
| SCHEMBL7853609 | 0.76 | REN (0.39) | CYP1A2CYP3A4CYP2D6TSHRGRIN2D | |
| SCHEMBL7991452 | 0.76 | REN (0.39) | CYP1A2CYP3A4CYP2D6TSHRGRIN2D | |
| SCHEMBL583721 | 0.75 | CYP1A2 (0.58) | IDO1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL5732849 | 0.75 | GRIN2B (0.40) | IDO1CYP1A2CYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL8017800 | 0.74 | CYP1A2 (0.56) | IDO1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL6064058 | 0.74 | CYP1A2 (0.61) | IDO1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL4131831 | 0.71 | SLC6A4 (0.63) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL10454919 | 0.71 | KCNA5 (0.49) | TSHRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303602-B1 | USEFUL AS ANALGESIC, ANESTHETIC, ANTI-INFLAMMATORY OR NEUROPROTECTIVE AGENT, OR FOR THERAPY OF ARTHRITIS, STROKE OF FUNCTIONAL BOWEL DISEASE | PFIZER INC. | 2001-10-16 | — | — | US | disclosed |