Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ICMT | O60725 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.38 |
| ▸ | FNTB | P49356 | 2/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985395 | 0.91 | GAA (0.43) | GAANR1H2NR1H3HPGDSMN1; SMN2 | |
| SCHEMBL7974584 | 0.91 | GAA (0.56) | GAANR1H2NR1H3ALDH1A1TP53 | |
| SCHEMBL7984454 | 0.89 | GAA (0.42) | GAA | |
| SCHEMBL7974478 | 0.88 | LMNA (0.43) | GAAALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL7985850 | 0.85 | GAA (0.49) | GAANR1H2NR1H3TP53 | |
| SCHEMBL7988594 | 0.85 | TP53 (0.44) | GAAICMTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7985336 | 0.85 | PIK3CA (0.42) | GAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7974018 | 0.84 | GAA (0.53) | GAANR1H2NR1H3ALDH1A1TP53 | |
| SCHEMBL7975267 | 0.84 | SMN1; SMN2 (0.46) | GAANR1H3ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7985348 | 0.84 | GAA (0.53) | GAANR1H2NR1H3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |