Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974093 | 0.96 | GAA (0.48) | GAAABCG2NR1H2NR1H3TP53 | |
| SCHEMBL7985850 | 0.93 | GAA (0.49) | GAAABCG2NR1H2NR1H3TP53 | |
| SCHEMBL7974584 | 0.92 | GAA (0.56) | GAAABCG2NR1H2NR1H3TP53 | |
| SCHEMBL7973626 | 0.90 | SMN1; SMN2 (0.45) | YTHDC1GLAHTTUBE2NSMN1; SMN2 | |
| SCHEMBL7985378 | 0.89 | TSHR (0.47) | GAAABCG2NR1H2NR1H3TP53 | |
| SCHEMBL7985577 | 0.88 | ABCG2 (0.46) | GAAABCG2NR1H2NR1H3TP53 | |
| SCHEMBL7984696 | 0.88 | GAA (0.47) | GAAABCG2NR1H2NR1H3TP53 | |
| SCHEMBL7991543 | 0.88 | GAA (0.47) | GAAABCG2NR1H2NR1H3TP53 | |
| SCHEMBL7974018 | 0.88 | GAA (0.53) | GAAABCG2NR1H2NR1H3TP53 | |
| SCHEMBL7974194 | 0.87 | ABCG2 (0.48) | GAAABCG2NR1H2NR1H3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |