Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725280 | 0.86 | SPR (0.33) | ABCC1GAAHSD17B10NOTUMMAPT | |
| SCHEMBL6723909 | 0.82 | NOTUM (0.31) | ABCC1NOTUMMAPT | |
| SCHEMBL8900556 | 0.82 | ABCC1 (0.30) | ABCC1NOTUMMAPT | |
| SCHEMBL8129913 | 0.80 | ABCC1 (0.32) | ABCC1HSD17B10MAPTKDM4EHPGD | |
| SCHEMBL9004023 | 0.79 | — | — | |
| SCHEMBL8402382 | 0.76 | — | — | |
| SCHEMBL8900199 | 0.76 | GAA (0.30) | GAA | |
| SCHEMBL6725615 | 0.75 | VEGFA (0.39) | GAAHSD17B10CA2 | |
| SCHEMBL6772501 | 0.73 | KDM4E (0.35) | ABCC1GAAHSD17B10NOTUMMAPT | |
| SCHEMBL6725568 | 0.70 | CYP4F2 (0.37) | GAAMAPTKMT2ATDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297196-B1 | HETEROCYCLIC COMPOUNDS WITH KETONE GROUPS AND OXIMES, PHOSPHONATES OR PHOSPHATES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-10-02 | — | — | US | disclosed |