SCHEMBL8900199

SCHEMBL8900199

C=CCOC1CCS(=O)(=O)c2c(C)cc(C(=O)O)c(C)c21

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.30
TSHR P16473 1/20 0.30
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9004023 0.86
SCHEMBL8402382 0.83
SCHEMBL8900556 0.82 ABCC1 (0.30)
SCHEMBL6725280 0.78 SPR (0.33) GAA
SCHEMBL7974618 0.76 ABCC1 (0.32) GAA
SCHEMBL6723909 0.75 NOTUM (0.31)
SCHEMBL9004086 0.72 SPR (0.37) TSHR
SCHEMBL8129913 0.71 ABCC1 (0.32) TSHR
SCHEMBL8901538 0.71 AKR1C2 (0.31)
SCHEMBL8899776 0.70 RXRA (0.37) RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0810227-A1 ISOXAZOLE DERIVATIVES IDEMITSU KOSAN COMPANY LIMITED (JP) 1997-12-03 EP disclosed