SCHEMBL6772501

SCHEMBL6772501

Cc1cc(C(=O)O)c(C)c2c1S(=O)(=O)CC2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
SPR P35270 1/20 0.35
ABCC1 P33527 1/20 0.35
GAA P10253 2/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 2/20 0.32
GPR35 Q9HC97 1/20 0.32
NOTUM Q6P988 1/20 0.32
LMNA P02545 1/20 0.31
CYP2C9 P11712 1/20 0.31
PSMD14 O00487 1/20 0.31
HSP90AA1 P07900 1/20 0.31
MMP2 P08253 1/20 0.31
THRB P10828 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6771639 0.86 SPR (0.34) KDM4ESPRABCC1GAAHPGD
SCHEMBL8133758 0.80 SPR (0.42) KDM4EMEN1KMT2ATDP1SPR
SCHEMBL6768806 0.79 SPR (0.48) SPR
SCHEMBL8870363 0.74 SPR (0.36) MEN1KMT2ASPRALDH1A1
SCHEMBL8870369 0.74 SPR (0.36) MEN1KMT2ASPRALDH1A1
SCHEMBL7974618 0.73 ABCC1 (0.32) KDM4EMEN1KMT2ATDP1SPR
SCHEMBL6725280 0.73 SPR (0.33) KDM4EMEN1KMT2ATDP1SPR
SCHEMBL6725582 0.73 RXRA (0.34) KDM4EMEN1KMT2ATDP1ABCC1
SCHEMBL6895329 0.72 HAAO (0.35) LMNACYP2C9GRM1
SCHEMBL8897799 0.72 ABCC1 (0.36) KDM4EMEN1KMT2ATDP1ABCC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6756343-B1 CONTROLLING RICE PADDY FIELD WEEDS AT LOW DOSAGE DOSE; PLANT SAFENING IDEMITSU KOSAN CO., LTD. (JP) 2004-06-29 US disclosed
US-20040002425-A1 Triketone derivatives and herbicides IDEMITSU KOSAN CO., LTD. (JP) 2004-01-01 US disclosed
EP-1120413-A1 TRIKETONE DERIVATIVE AND HERBICIDE IDEMITSU KOSAN COMPANY LIMITED (JP) 2001-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040002425-A1 Triketone derivatives and herbicides SYMPK, STK36, STK32A KDM4E 932/4885MEN1 4694/4885KMT2A 516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.