Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 2/20 | 0.43 |
| ▸ | PARN | O95453 | 1/20 | 0.43 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988183 | 0.93 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL7974056 | 0.91 | HPGD (0.47) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL7984876 | 0.91 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL7988452 | 0.90 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL7974274 | 0.89 | CNOT7 (0.45) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL7984195 | 0.88 | HPGD (0.45) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL7974306 | 0.88 | HPGD (0.45) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL7973916 | 0.88 | LMNA (0.43) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL7974850 | 0.87 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL7984463 | 0.87 | KDM4E (0.53) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |