Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | GUSB | P08236 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | PARN | O95453 | 1/20 | 0.44 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985798 | 0.89 | GUSB (0.53) | SMN1; SMN2ALDH1A1KMT2AHPGDGUSB | |
| SCHEMBL7985535 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1KMT2AHPGDGUSB | |
| SCHEMBL7974644 | 0.87 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1KMT2AHPGDACP1 | |
| SCHEMBL7975265 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1KMT2AHPGDPARN | |
| SCHEMBL7975119 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1KMT2AHPGDGUSB | |
| SCHEMBL7984453 | 0.83 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1KMT2AHPGDGUSB | |
| SCHEMBL7974857 | 0.81 | CNOT7 (0.52) | SMN1; SMN2ALDH1A1KMT2AHPGDGUSB | |
| SCHEMBL7975129 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1KMT2AHPGDPARN | |
| SCHEMBL7974445 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1KMT2AHPGDPARN | |
| SCHEMBL7985490 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1KMT2AHPGDPARN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |