Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 16/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 14/20 | 0.53 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.51 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7972683 | 0.99 | L3MBTL3 (0.52) | L3MBTL3L3MBTL1MBTD1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7977435 | 0.86 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1MBTD1ALDH1A1HPGD | |
| SCHEMBL7961213 | 0.82 | HRH3 (0.57) | — | |
| Hydrochloric Acid SCHEMBL7971441 | 0.81 | HRH3 (0.56) | — | |
| SCHEMBL7961432 | 0.81 | HPGD (0.54) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7961401 | 0.77 | TP53 (0.49) | L3MBTL1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14287744 | 0.76 | L3MBTL3 (0.67) | L3MBTL3L3MBTL1MBTD1ALDH1A1TP53BP1 | |
| SCHEMBL7961494 | 0.76 | MAPT (0.56) | L3MBTL1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7971231 | 0.74 | GPR119 (0.53) | L3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7974351 | 0.74 | TP53 (0.51) | L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| EP-0968164-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998033758-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-06 | — | — | WO | disclosed |