SCHEMBL7974741

SCHEMBL7974741

O=[C]N(c1cccc(Cl)n1)C1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.35
IDH1 O75874 1/20 0.34
LMNA P02545 4/20 0.33
TRPM8 Q7Z2W7 2/20 0.33
TSHR P16473 3/20 0.33
HPGD P15428 1/20 0.33
CYP3A4 P08684 1/20 0.33
AGER Q15109 1/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
CYP1A2 P05177 2/20 0.32
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
CYP2D6 P10635 1/20 0.32
ALOX15 P16050 1/20 0.32
NFKB1 P19838 1/20 0.32
HTR3A P46098 1/20 0.32
HTR3D Q70Z44 1/20 0.32
HTR3C Q8WXA8 1/20 0.32
P2RX7 Q99572 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4118367 0.69 CYP2C9 (0.40) ALDH1A1LMNATSHRHPGDCYP3A4
SCHEMBL14855820 0.68 MEN1 (0.46) ALDH1A1LMNATRPM8TSHRHPGD
SCHEMBL2393892 0.68 MEN1 (0.46) ALDH1A1LMNATRPM8TSHRHPGD
SCHEMBL14855771 0.66 MEN1 (0.44) ALDH1A1LMNATRPM8HPGDCYP3A4
SCHEMBL7971901 0.65 CYP3A4 (0.44) ALDH1A1TSHRCYP3A4HTR3EHTR3B
SCHEMBL14855591 0.64 MEN1 (0.41) ALDH1A1LMNATRPM8HPGDCYP3A4
SCHEMBL5042156 0.64 HRH3 (0.47) ALDH1A1LMNACYP2D6KDM4ESMN1; SMN2
SCHEMBL7975175 0.64 HCAR2 (0.34) TSHRHPGD
SCHEMBL25601865 0.63 HTR1A (0.46) IDH1TSHRCYP3A4MEN1KMT2A
SCHEMBL3939737 0.62 NPC1 (0.32) SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001017965-A2 CYANOPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO disclosed