Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3939777 | 0.80 | HPGD (0.30) | — | |
| SCHEMBL18674674 | 0.64 | — | — | |
| SCHEMBL9057205 | 0.64 | G6PC1 (0.39) | SMN1; SMN2MAPK1 | |
| SCHEMBL7974741 | 0.62 | ALDH1A1 (0.35) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5708677 | 0.62 | RAB9A (0.44) | NPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL1118960 | 0.59 | — | — | |
| SCHEMBL28937389 | 0.59 | RAB9A (0.36) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21610736 | 0.59 | RAB9A (0.44) | NPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL14855591 | 0.59 | MEN1 (0.41) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14855771 | 0.57 | MEN1 (0.44) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049536-A2 | POLYCYCLIC VIRAL INHIBITORS | GENELABS TECHNOLOGIES, INC. (US) | 2009-04-22 | — | — | EP | disclosed |
| EP-2044083-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008011521-A2 | POLYCYCLIC VIRAL INHIBITORS | GENELABS TECHNOLOGIES, INC. (US) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008008907-A2 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. (US) | 2008-01-17 | — | — | WO | disclosed |
| WO-2008008912-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. (US) | 2008-01-17 | — | — | WO | disclosed |