Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | BMP1 | P13497 | 2/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27890820 | 0.85 | CA1 (0.50) | CA1CA2ENPP2ALDH1A1LMNA | |
| SCHEMBL1429021 | 0.83 | CA1 (0.68) | CA1CA2ALDH1A1LMNANPSR1 | |
| SCHEMBL8072061 | 0.83 | ALDH1A1 (0.57) | CA1CA2ENPP2ALDH1A1LMNA | |
| SCHEMBL2653485 | 0.81 | ALDH1A1 (0.64) | CA1CA2ENPP2ALDH1A1LMNA | |
| SCHEMBL13055884 | 0.79 | IDO1 (0.57) | CA1CA2ALDH1A1LMNANPSR1 | |
| SCHEMBL28294562 | 0.77 | MMP12 (0.58) | CA1CA2ALDH1A1LMNANPSR1 | |
| SCHEMBL935251 | 0.76 | ALDH1A1 (0.54) | CA1CA2ENPP2ALDH1A1LMNA | |
| SCHEMBL1434498 | 0.76 | CA2 (0.64) | CA1CA2ENPP2PTGS2KCNJ1 | |
| SCHEMBL27109801 | 0.76 | KCNJ1 (0.43) | CA1CA2ENPP2ALDH1A1LMNA | |
| SCHEMBL28327299 | 0.76 | CYP4F2 (0.66) | ALDH1A1LMNANPSR1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |