Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992105 | 0.92 | YAP1 (0.41) | YAP1ADORA1NR1D1ITGB3ITGA2B | |
| SCHEMBL7986612 | 0.91 | ITGB3 (0.40) | YAP1ADORA1NR1D1ITGB3ITGA2B | |
| SCHEMBL7985585 | 0.88 | ADORA1 (0.38) | YAP1ADORA1NR1D1ITGB3ITGA2B | |
| SCHEMBL7985559 | 0.88 | ADORA1 (0.50) | ADORA1ITGB3ITGA2BP2RX7LMNA | |
| SCHEMBL7992026 | 0.85 | ITGB3 (0.35) | ADORA1ITGB3ITGA2BP2RX7KMT2A | |
| SCHEMBL7986064 | 0.80 | ADORA1 (0.50) | ADORA1P2RX7ALDH1A1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7986192 | 0.80 | ITGB3 (0.39) | ADORA1ITGB3ITGA2BP2RX7ALDH1A1 | |
| SCHEMBL7985777 | 0.80 | ITGB3 (0.41) | ADORA1ITGB3ITGA2BP2RX7ALDH1A1 | |
| SCHEMBL7988424 | 0.79 | ITGB3 (0.57) | ADORA1ITGB3ITGA2BP2RX7ALDH1A1 | |
| SCHEMBL7975424 | 0.79 | ITGB3 (0.40) | ADORA1ITGB3ITGA2BP2RX7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |