Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974860 | 0.85 | YAP1 (0.40) | ITGB3ITGA2BITGA4P2RX7KMT2A | |
| Hydrochloric Acid SCHEMBL7986192 | 0.84 | ITGB3 (0.39) | ITGB3ITGA2BP2RX7MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7992078 | 0.81 | ITGB3 (0.35) | ITGB3ITGA2BP2RX7KMT2AADORA1 | |
| SCHEMBL7985559 | 0.80 | ADORA1 (0.50) | ITGB3ITGA2BITGA4P2RX7KMT2A | |
| SCHEMBL7992105 | 0.77 | YAP1 (0.41) | ITGB3ITGA2BITGA4KMT2AMCL1 | |
| SCHEMBL7986612 | 0.77 | ITGB3 (0.40) | ITGB3ITGA2BP2RX7KMT2AMCL1 | |
| SCHEMBL7988424 | 0.77 | ITGB3 (0.57) | ITGB3ITGA2BP2RX7MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7986317 | 0.76 | ITGB3 (0.56) | ITGB3ITGA2BP2RX7MEN1KMT2A | |
| SCHEMBL7992407 | 0.76 | ITGB3 (0.48) | ITGB3ITGA2BP2RX7MEN1KMT2A | |
| SCHEMBL7986354 | 0.76 | ITGB3 (0.47) | ITGB3ITGA2BP2RX7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |