Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.60 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665638 | 0.78 | HCAR2 (0.67) | HCAR2SMYD3MKNK1MKNK2PKM | |
| SCHEMBL27417421 | 0.78 | HCAR2 (0.67) | HCAR2SMYD3MKNK1MKNK2PKM | |
| SCHEMBL44147 | 0.77 | TPMT (0.52) | CES1ACHE | |
| SCHEMBL23181527 | 0.77 | HCAR2 (0.41) | HCAR2CES1ACHE | |
| SCHEMBL16600044 | 0.77 | POLB (0.60) | HCAR2SMYD3 | |
| SCHEMBL3473330 | 0.77 | HCAR2 (0.60) | HCAR2SMYD3CES1ACHE | |
| SCHEMBL24198754 | 0.77 | HCAR2 (0.55) | HCAR2SMYD3MKNK1MKNK2PKM | |
| SCHEMBL486309 | 0.75 | HCAR2 (1.00) | HCAR2SMYD3MKNK1MKNK2 | |
| SCHEMBL4196968 | 0.75 | HCAR2 (0.69) | HCAR2SMYD3MKNK1MKNK2PKM | |
| SCHEMBL29944817 | 0.75 | HCAR2 (1.00) | HCAR2SMYD3MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |